Bioprocess Development / Contract Production
Fermentation process development from pilot to commercial-scale production
PROPHYTA provides the facilities and trained staff to develop, transfer, or scale up your solid-state fermentation process. PROPHYTA has developed a unique solid-state fermentation technology for production of filamentous fungi.
Out-source projects or increase capacity!
In the PROPHYTA-fermentation facilities we will optimize your production or develop a fermentation process that will improve the product’s performance – giving a competitive advantage on the market.
In addition to designing equipment and developing processes, PROPHYTA offers licences for its technology and expertise in solid-state fermentation technology.
As the principle of the PROPHYTA®L-Fermenter and the PROPHYTA®fermenters of industrial size is the same, a scale up of an optimised bioprocess is always possible. PROPHYTA offers its expertise in production scale up, technology transfer and project management if a scale up is desired. After succeeding with the PROPHYTA®L-Fermenter the scale up usually begins with the medium sized PROPHYTA®Pilot Fermenter with external peripheral equipment (“pilot phase” of the scale up). In the final phase production will be set up on the desired commercial scale. The PROPHYTA®fermenters of industrial size can be licensed in order to build up a production unit. Alternatively it is possible to have the production done by PROPHYTA on commission.
Applications of Solid-State Fermentation
|Examples of suitable fungi|
|Production of Biocontrol agents|
|Production of Enzymes|
|CELLULASES, XYLANASE||Trichoderma spp.|
Pleurotus ostreatus, Trametes spp.
|GALCTOSIDASES AND PECTINASES||Aspergillus spp.|
|Production of Organic acids|
|Citric Acid||Aspergillus niger|
|Lactic Acid||Rhizopus oryzae|
|Production of Secondary Metabolites|
|Giberellic acid||Fusarium moniliforme|
|Ergot Alkaloids||Claviceps spp.|
|Antibiotics||depends on the antibiotic group|
|Production of Fungi Forming Ectomycorrhizae|
|Production of Mushroom Spawn|
|Production of Fungal Inoculum|
|Cheese production||Penicillium roquefortii
|For resistance screening in plant breeding or fungicide testing||Sclerotinia spp.
Advantages of PROPHYTA’s Solid-State Fermentation Technology
- Contamination-free growth conditions for long periods of time, which allows the production of even slow-growing fungi
- Microprocessor-controlled fermentation with data collection
- Cost effective
- High production capacity after scale up